A prescription can be clinically appropriate, sent to the pharmacy, and ready for pickup. The patient can still never fill it. A study published in PLOS Digital Health examined whether personalized SMS reminders could improve medication adherence and reduce hospital readmissions among patients with congestive heart failure. The retrospective study included 1,276 patients, with a […]
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Every day, healthcare practitioners diagnose conditions, explain treatment options, and recommend evidence-based interventions. The clinical plan may be sound. The patient may leave the appointment intending to follow it. Then the patient goes home. Questions surface. Details become harder to remember. A family member raises concerns. A side effect appears. What felt clear inside the […]
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A figure presented at ENDO 2026 in Chicago has stayed with me for weeks. In the largest claims analysis of its kind, researchers tracked more than 60,000 adults who started a GLP-1 for type 2 diabetes. By the two-year mark, most had stopped at some point. Here is the part our industry tends to skip […]
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When a patient leaves the exam room, the confidence they felt sitting across from their physician often fades by the time they get home. That hesitation is where high-end specialty procedures get postponed, second-guessed, or quietly abandoned. Alliance Orthopedics is doing something about it. The multi-location specialty practice has announced a two-year, practice-wide partnership with […]
Read moreThe Abandonment Rate is Getting Worse. Here’s Why. *By Bob Miglani, CEO of Hoot | Former Pfizer Leader, 23 Years* Watch video clip here: — I spent 23 years at Pfizer watching something that should have been unacceptable become normalized. A drug gets approved. Clinical trials prove it works. Physicians prescribe it. And then somewhere […]
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Three new research signals reveal a widening chasm between prescription intent and patient action, and point toward what actually closes it. Every day, physicians write prescriptions that patients never fill. Some never even pick them up. Others start, stop, and disappear from therapy within 90 days. The clinical encounter works. The commercial infrastructure behind it […]
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The Communication Gap in Dry Eye Care Dry eye disease continues to grow as one of the most common and frustrating conditions seen in eye care practices today. At the same time, many providers still face the same challenge: patients often do not fully understand the severity of their condition or why treatment matters. For […]
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Gross-to-net pressure has become one of the defining commercial realities in specialty pharma. According to Hoot’s latest executive briefing, manufacturers gave back an estimated $356 billion in rebates, government discounts, 340B obligations, and chargebacks before net revenue was ever recognized. That number alone changes how commercial leaders think about growth. The challenge is no longer […]
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AI has moved out of the experimental phase in healthcare. It is no longer something teams are exploring on the side. It is now embedded in how organizations think about patient engagement, communication, and scale. But as adoption accelerates, something more subtle is happening beneath the surface. Patients are not just receiving more information. They […]
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Over the past week, several new data points reinforced something that has been quietly undermining patient engagement strategies for years. It is not that healthcare organizations are failing to engage patients. It is that they are measuring the wrong signals entirely. A 2026 study published in BMC Health Services Research reaffirmed that the quality of […]
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